Hello, I'm glad you chose to learn more about Niacinex®! I'm Doctor Bogdan Popa, and I created Niacinex®. It's a High-Dose 500mg Advanced Matrix Extended Release Niacin. 

Niacinex® minimizes or eliminates the unpleasant side effect of skin “flushing” experienced with regular niacin.

But there are a few more things you need to know... 

You can get a 25% discount on your next Niacinex® purchase on Amazon by clicking here (but I hope you will also stick around to read on for a few more minutes...)

Also, Niacin can help you significantly lower bad cholesterol (LDL and VLDL), increase good cholesterol (HDL), and decrease Lp(a), live longer, look and feel years younger, sleep better, and ease cravings for alcohol and other addictive substances. 

You’ve probably heard that high-dose Niacin can do wonders for your cholesterol levels. While that's true, it can do so much more...

Niacin accomplishes all of this by increasing the levels of an essential molecule present in all of our cells called NAD+, the main molecule that drives energy formation in the form of ATP.

Flushing can be an unpleasant side effect of plain Niacin supplementation. Unfortunately that's why the majority of people stop taking it, despite some of its amazing benefits. That's what inspired Niacinex®. By following the recommended dosage, you can minimize flushing and enjoy the benefits without discomfort. 

I  hope you love the consistent results you get from Niacinex®!

In health,

Bogdan Popa, MD

Functional Medicine, Cert. Practitioner & Board Certified Anesthesiologist 

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Why Niacinex®?
Extensive clinical research has demonstrated that high dose nicotinic acid, as found in Niacinex®, helps maintain healthy cholesterol levels. However, this formula does more than just that. It can also:
  • Energize your body and boosts metabolism
  • ​Support heart health
  • ​Enhance brain function and memory
  • ​Improve skin health and reduce inflammation
  • ​Regulate blood sugar levels and aid digestion
  • ​Strengthen the immune system & fight infection
  • ​Support healthy vision, DNA repair & gene integrity
When you choose Niacinex®, you can expect optimal absorption and purity. 

Our safe, exclusive vegetable-based wax ingredient melts at body temperature and mimics natural food processing for an extended release. Niacinex™ is the gentle and effective long-term solution to support your overall well-being.

Free from Common Allergens, Packed with Quality.
We understand the significance of providing a product that caters to various dietary needs. That's why Niacinex® is suitable for vegans and vegetarians. It is also free from common allergens (gluten, dairy, soy, eggs, and nuts), ensuring that a broader audience can benefit from our exceptional formula. 

Niacinex® is devoid of salt, sugar, starch, artificial flavorings, and preservatives, offering a pure and clean supplement you can rely on.

Additionally, this unique formula is made in the USA in a GMP-certified facility and is third-party certified. We post the results of the Certificate of Analysis here so you can see exactly what's inside each tablet. 
Benefits of Niacinex® Extended High-Dose Niacin
As I mentioned above, the advantages go far beyond cholesterol balance and heart health. Click any of the sections below to learn more about the incredible health benefits of Niacin. 

Let's talk about Cholesterol. You have heard that high dose Niacin, as nicotinic acid, will naturally lower your total cholesterol. In addition, the benefits include increased HDL, your good cholesterol, while simultaneously lowering your bad cholesterol, LDL. That’s truly amazing since even the most popular prescription medications (e.g. Atorvastatin and Lovastatin) only lower total cholesterol and have a lot of unpleasant side effects like brain fog, muscle pain, and elevated liver enzymes among others.

Even more impressively, high dose Niacin works to lower the levels of a dangerous fat particle called “lipoprotein a “ or “Lp(a)” for short.

High levels of Lp(a) are genetically inherited in 20-30% of people and levels over 30 mg/dl are considered an independent and direct risk for cardiovascular events like heart attacks and strokes. 

Like Niacin, a new class of prescription cholesterol lowering medications called PCSK9 inhibitors can help lower Lp(a) by 25% but again they are expensive, they require an injection every few weeks and they can cause muscle pain and fatigue as well as kidney and liver problems. 

Why go through this much trouble when high dose Niacin can lower your Lp(a) by 20-80% and therefore your risk of heart attack and stroke naturally with none of these nasty side effects?

Niacin (Vitamin B3) is the parent, or precursor, for NAD+ (nicotinamide adenine nucleotide) which is a molecule present in every one of our cells that is responsible for all energy production (ATP) in mitochondria in all cells. Our cells process niacin (b3) to synthesize NAD+.

Without NAD+ there is no life. Without ADEQUATE amounts of NAD+ we don’t live or feel well.

As we age levels of NAD+ decrease dramatically, which is of concern because NAD+ is an essential molecule for a set of enzymes in our bodies called sirtuins.

Sirtuins are “anti aging” protein enzymes in all of our cells that use NAD+ (which is made from Niacin, also known as Vitamin B3) and “turn off” aging, inflammation, fat synthesis, fat storage and insulin resistance related genes. With the help of NAD+, sirtuins help to guard our genes by continuously repairing damaged DNA.

Taken together, the effect sirtuins have on our bodies is that they keep us “young”. But without enough NAD+ (and therefore insufficient niacin) sirtuins would stop working entirely. Unfortunately, levels of NAD+ decrease substantially as we age. That's why it's extremely important to support NAD+ levels by taking Niacinex™.

Another effect of NAD+ is to reduce cravings for alcohol and other addictive substances, like drugs. 

Alcohol recovery clinics clinics, like the one Dr. Ken Starr runs, use high dose intravenous NAD+ infusions to decrease “cravings” for alcohol and drugs use as well as dramatically reduce withdrawal symptoms. On his website Dr. Ken Starr mentions that we now know that people with addiction to drugs and alcohol have an NAD+ deficiency especially in the “reward” parts of the brain that secretes dopamine. When NAD+ levels are restored, the cravings simply go away as well as withdrawal symptoms. 

But high dose NAD+ infusions are expensive, they are invasive (you have to go to a clinic for and be attached to an IV for hours) and inconvenient. The far easier way to achieve adequate NAD+ levels is to take high dose Niacin orally. High dose niacin for the treatment of addiction is described in the book "Niacin: The Real Story" by Abram Hoffer.

Here we learn that even the early founders of AAA were using up to 3000 mg of Niacin per day in divided doses to reduce cravings and anxiety and maintain sobriety. Of course they were using “plain” Niacin which means that they had to get past the skin flushing side effect. This is no longer an issue with Niacinex™ since the extended gradual release greatly diminishes and eliminates this issue. 

A word of caution however: do not independently increase your dose of Niacin to levels higher than the 500 mg per day without first working with a doctor who can conduct periodic labs. In very rare cases, doses higher than 1500 mg per day can cause an elevation of liver enzymes. 

A serious insufficiency of niacin has been linked to cognitive decline, such as memory impairment and senility. Niacin is believed to safeguard brain cells against stress and harm. 

One study of 3,718 males and females aged 65 and above were monitored for 6 years, employing dietary surveys and cognitive evaluations. A protective effect from Alzheimer's disease and cognitive decline was noticed when comparing the highest and lowest levels of niacin intake. (Niacin – Vitamin B3, 2023)

The Coronary Artery Risk Development in Young Adults (CARDIA) investigation also reviewed 3,136 males and females aged 18-30 for a maximum of 25 years. The study gauged the consumption of B vitamins from both diet and supplements, alongside cognitive performance. A greater consumption of B vitamins, particularly niacin, during early adulthood was linked to enhanced scores in cognitive function during midlife. (Qin et al., 2017)

Niacin helps improve circulation and has been shown to suppress inflammation. 

When it comes to your skin, Niacin helps protect it by reducing stress and inflammation, improves the structure of the skin, and prevents dark spots. Niacin can help protect skin cells from sun damage and may help prevent certain types of skin cancer as well. 

One study in over 300 people at high risk of skin cancer found that taking 500 mg of nicotinamide twice daily reduced rates of nonmelanoma skin cancer compared to a control, attenuates oxidative stress and inflammatory response, enhances extracellular matrix and skin barrier, and inhibits the pigmentation process in the skin. (Starr, 2015)

Tailored for Your Well-being, Suitable for All.
Niacinex® is designed for both men and women seeking advanced nutritional support for heart health, cholesterol balance, and overall well-being. With our extended-release Niacin, you can unlock the potential to achieve a healthier version of yourself.
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